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Image Search Results
Journal: Communications Biology
Article Title: Aromatic patch in whiB-like transcription factors facilitates primary sigma factor interaction in mycobacterium tuberculosis
doi: 10.1038/s42003-026-09698-5
Figure Lengend Snippet: A – C Representative results for Isothermal titration calorimetry (ITC) assay of the interactions between σ A 4 and Mtb Wbls as indicated. The calorimetric titration is shown in the top panel (the raw data in Supplementary DataSet ), with the integrated injection heat derived from the titration and the best-fit curve (dash lines) of a simple 1:1 interaction model shown in the bottom ( D ) Summary of the binding parameters from the best fit, including the association constant ( K a ), dissociation constant ( K d ), changes in enthalpy (ΔH) and entropy (ΔS) upon binding, and the goodness of the fit (Chi /DoF).
Article Snippet: The analysis for the ITC was done using
Techniques: Isothermal Titration Calorimetry, Titration, Injection, Derivative Assay, Binding Assay